Two unaffected parents already have one child with cystic fibrosis (a recessive condition). What is the probability that their next two children are both unaffected?

Answer and explanation

Correct answer: B.

  1. Step 1: Both parents must be carriers, so each child has probability of being affected and of being unaffected.
  2. Step 2: Children are independent: .
Answer
.
Why not the others: : is the probability for a single child. : is the probability that both are affected. : is the probability that exactly one is affected.

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