Answer and explanation

Correct answer: D. A random change in the base sequence of DNA

  1. Step 1: Mutations change the DNA sequence.
  2. Step 2: They can create new alleles.
Answer
A random change in the base sequence of DNA.
Why not the others: A change in the weather that affects organisms: this is environmental. A copy of a gene in another cell: this is not a mutation. The death of a cell: this is apoptosis.

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What is a mutation? | National 5 (Scotland)