UKMLA Applied Knowledge Test (MSRA-style single best answer) · Neurology, Mental Health, Ophthalmology and ENT

Neurology

15 practice questions, each with the answer and an explanation.

Practise Neurology now

Random questions from this topic, one at a time. You see the answer and the explanation straight after each one.

All 15 questions

  1. A woman has sudden right arm weakness and slurred speech that began 2 hours ago. A non-contrast CT head shows no haemorrhage and her blood pressure is acceptable. What is the most appropriate treatmen…
  2. A man has had a brief episode of transient left hand weakness that resolved fully within 30 minutes. He is neurologically normal now. What does NICE recommend?
  3. A 38-year-old has a sudden thunderclap headache 8 hours ago, with neck stiffness. A CT head performed now is reported as normal. What is the most appropriate next step according to NICE?
  4. A young adult has fever, headache, neck stiffness and a non-blanching rash. A GP has seen the patient at home. What should be given before transfer?
  5. A 72-year-old woman has a new temporal headache, jaw claudication, scalp tenderness and an ESR of 95 mm/hr. What is the most appropriate immediate treatment?
  6. A 22-year-old woman with generalised tonic-clonic seizures wants to start treatment. Why is sodium valproate not first choice?
  7. According to DVLA rules for a car driver (group 1), what is the usual minimum period without driving after a first unprovoked seizure with no abnormality found on investigation?
  8. A 28-year-old woman has a relapse of multiple sclerosis with new visual loss and leg weakness. What is the usual treatment for an acute relapse?
  9. A man develops ascending leg weakness with absent reflexes two weeks after a diarrhoeal illness. What is the most important monitoring investigation in the first days?
  10. Which regimen is recommended for acute migraine in an adult according to NICE?
  11. A woman with sudden onset left facial droop including forehead weakness and inability to close the left eye has no limb weakness or other deficit. What is the likely diagnosis and treatment?
  12. A man with back pain develops urinary retention, saddle numbness and bilateral leg weakness. What is the right management?
  13. A woman has fatigable ptosis and diplopia that worsens in the evening. Which antibody is most commonly found?
  14. An elderly man on warfarin falls and, two weeks later, becomes drowsy and confused. CT head shows a crescent-shaped collection across the cerebral convexity. What is the diagnosis?
  15. An 80-year-old has fluctuating cognition, well-formed visual hallucinations of children and mild parkinsonism. He becomes severely rigid and unresponsive after haloperidol. Which diagnosis explains th…

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