What is the term for a permanent alteration in the nucleotide sequence of an organism's genome?

Answer and explanation

Correct answer: A. Mutation

  1. Step 1: Genetic information is encoded in DNA nucleotide sequences.
  2. Step 2: A mutation is any permanent change in the nucleotide sequence resulting from replication errors, mutagens, or viral insertion.
Answer
Mutation.
Why not the others: 'Transcription' is synthesizing RNA from a DNA template; 'Translation' is synthesizing protein from mRNA; 'Replication' is copying the entire DNA genome.

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