A woman on long-term prednisolone presents vomiting, hypotensive and drowsy after missing doses with an intercurrent illness. What is the most appropriate treatment?

Answer and explanation

Correct answer: C. Intravenous hydrocortisone and intravenous fluid resuscitation

  1. Step 1: Long-term steroids suppress the adrenal axis, so illness and missed doses can cause adrenal crisis. Step 2. Hydrocortisone and fluids are given without waiting for tests, as the condition is life-threatening. Answer: Intravenous hydrocortisone and intravenous fluid resuscitation. Why not the others: Oral steroids will not be absorbed if she is vomiting and are insufficient in crisis. Insulin is irrelevant, and levothyroxine is for hypothyroidism.

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