A man with benign prostatic enlargement has taken finasteride for a year. His PSA is 2.4 ng/mL. How should it be interpreted?
Answer and explanation
Correct answer: C. About double the measured value
- Step 1: 5-alpha reductase inhibitors reduce prostate volume and lower serum PSA. Step 2. After about six months the PSA falls by roughly half, so the measured value is doubled for interpretation, and a rise on treatment is itself concerning. Answer: About double the measured value. Why not the others: The drug does alter PSA. Halving would underestimate the true level. PSA is still measurable and remains useful.
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