What term describes chromosomes that fail to separate properly during anaphase I or anaphase II of meiosis, causing aneuploidy such as Down syndrome?

Answer and explanation

Correct answer: B. nondisjunction

  1. Step 1: Nondisjunction is the failure of homologous chromosomes or sister chromatids to separate, resulting in gametes with n+1 or n-1 chromosomes (e.g. Trisomy 21). Answer: nondisjunction. Why not the others: Translocation is swapping segments between non-homologs.

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