Where does the enzymatic Urea Cycle (Ornithine Cycle) take place in the human body? (Hard)

Answer and explanation

Correct answer: C. In the Liver

  1. Step 1: The urea cycle (discovered by Krebs and Henseleit) synthesizes urea from CO2 and NH3. Step 2. The first two reactions occur in the mitochondrial matrix of hepatocytes, while subsequent reactions take place in the hepatocyte cytoplasm. Answer: In the Liver (partly in mitochondria and partly in cytoplasm). Why not the others: Kidneys excrete urea formed by liver; small intestine absorbs nutrients; bone marrow produces blood cells.

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