What is the physiological osmolarity of human blood plasma (Hard) and isotonic saline solution?
Answer and explanation
Correct answer: D. Approximately 290 to 300 mOsm/L
- Step 1: Normal human plasma osmolarity is tightly regulated between 285 and 295 mOsm/kg. Step 2. Isotonic clinical intravenous saline (0.9% w/v NaCl) closely matches this at approximately 308 mOsm/L. Answer: Approximately 290 to 300 mOsm/L. Why not the others: 100 mOsm/L is severely hypotonic (causing erythrocyte hemolysis); 600 mOsm/L is severely hypertonic (causing cellular crenation); 50 mOsm/L is near pure water.
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