Which fat-soluble vitamin is essential for blood coagulation, functioning as a cofactor for gamma-glutamyl carboxylase in the liver?
Answer and explanation
Correct answer: B. Vitamin K
- Step 1: Clotting factors II (prothrombin), VII, IX, and X require post-translational carboxylation of glutamate residues to bind calcium. Step 2. Vitamin K acts as an indispensable cofactor for gamma-glutamyl carboxylase, enabling clotting factor activation. Answer: Vitamin K. Why not the others: Vitamin A is essential for retinal rhodopsin; Vitamin D regulates calcium absorption; Vitamin C is required for collagen proline hydroxylation.
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