Which vitamin deficiency causes the classical triad of Dementia, Diarrhea, and Dermatitis known as Pellagra?
Answer and explanation
Correct answer: B. Vitamin B3
- Step 1: Niacin (nicotinic acid) is the precursor for NAD+ and NADP+ redox coenzymes. Step 2. Severe dietary deficiency causes Pellagra, clinically characterized by the '4 Ds': diarrhea, dermatitis, dementia, and death. Answer: Vitamin B3 (Niacin). Why not the others: Vitamin B1 causes beriberi; Vitamin B2 causes cheilosis and angular stomatitis; Vitamin B6 causes peripheral neuropathy and sideroblastic anemia.
Practise more Organic Reactions, Biomolecules and Pharmaceutical Principles.
Free questions with an explanation for every one, and full timed Medical College Admission Test (Bangladesh) mock tests.
More Organic Reactions, Biomolecules and Pharmaceutical Principles questions
- Why is Phenol significantly more acidic than aliphatic alcohols like Ethanol? (Hard)
- What observation confirms the presence of Phenol when treated with neutral Ferric chloride (FeCl3) solution?
- What product is formed when Phenol is treated with excess Bromine water at room temperature?
- What is the active pharmaceutical chemical name of Aspirin, synthesized by acetylating salicylic acid?
- What is the major chemical constituent of 'Oil of Wintergreen', used as a topical analgesic ointment?
- Why is Sucrose (cane sugar) classified as a non-reducing disaccharide? (Hard)