During rapid sequence intubation, why is succinylcholine contraindicated in a patient who suffered severe full-thickness burns five days prior?
Answer and explanation
Correct answer: A. Catastrophic acute hyperkalemic cardiac arrest from up-regulated extrajunctional acetylcholine receptors
Answer: Catastrophic acute hyperkalemic cardiac arrest from up-regulated extrajunctional acetylcholine receptors.
Why not the others: Extrajunctional nicotinic receptor proliferation leads to massive potassium efflux upon depolarization; Succinylcholine is a depolarizing blocker with a short duration; Succinylcholine does not cause centrilobular hepatic necrosis; It does not induce hypocalcemic tetany.
Why not the others: Extrajunctional nicotinic receptor proliferation leads to massive potassium efflux upon depolarization; Succinylcholine is a depolarizing blocker with a short duration; Succinylcholine does not cause centrilobular hepatic necrosis; It does not induce hypocalcemic tetany.
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