Which intermolecular force is primarily responsible for stabilizing the alpha-helix and beta-pleated sheet secondary structures of proteins?

Answer and explanation

Correct answer: B. Hydrogen bonds between peptide amide groups

  1. Step 1: Secondary structures of proteins result from regular folding of the polypeptide backbone.
  2. Step 2: The folding is stabilized by hydrogen bonding between the carbonyl oxygen () and amide hydrogen () of peptide linkages.
Answer
Hydrogen bonds between peptide amide groups.
Why not the others: Disulfide bridges, hydrophobic interactions, and electrostatic salt bridges stabilize tertiary and quaternary three-dimensional protein structures.

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