Which cells function as professional antigen-presenting cells (APCs) capable of activating naive CD4+ T helper cells by expressing surface Class II Major Histocompatibility Complex (MHC II) molecules?
Answer and explanation
Correct answer: B. Dendritic cells, macrophages, and B lymphocytes
Professional antigen-presenting cells (APCs) constitutively or inducibly express MHC Class II molecules together with costimulatory molecules (CD80/CD86). The primary professional APCs are dendritic cells (the most potent activators of naive T cells), macrophages, and B lymphocytes.
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