A 65-year-old man has a slowly growing, painless prostate nodule and an elevated PSA. Where do prostate adenocarcinomas most commonly arise?
Answer and explanation
Correct answer: D. The peripheral zone
- Step 1: Most prostate cancers arise in the peripheral zone, which can be felt on rectal examination. Step 2. Benign prostatic hyperplasia arises in the transition zone. Answer: the peripheral zone. Why not the others: the transition zone is the site of hyperplasia, and the central zone and periurethral glands are rare sites.
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