A protein has a Hill coefficient greater than 1. What does this indicate about ligand binding?
Answer and explanation
Correct answer: D. Positive cooperativity
- Step 1: A Hill coefficient above 1 means that binding of one ligand makes the next binding easier. Step 2. Hemoglobin binding oxygen is the classic example. Answer: positive cooperativity. Why not the others: a value below 1 means negative cooperativity and a value of 1 means none.
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