How does antidiuretic hormone increase water reabsorption in the collecting duct?
Answer and explanation
Correct answer: D. By inserting aquaporin-2 channels into the apical membrane
- Step 1: ADH binds V2 receptors on collecting duct cells. Step 2. This triggers insertion of aquaporin-2, so water follows the osmotic gradient. Answer: inserting aquaporin-2 channels. Why not the others: blocking NKCC2 is the effect of loop diuretics.
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