MCAT (Medical College Admission Test) ยท Biological and Biochemical Foundations of Living Systems

Cell Biology, Genetics and Physiology

69 practice questions, each with the answer and an explanation.

Practise Cell Biology, Genetics and Physiology now

Random questions from this topic, one at a time. You see the answer and the explanation straight after each one.

All 69 questions

  1. Which organelle contains hydrolytic enzymes for intracellular digestion?
  2. Which organelle is mainly responsible for modifying, sorting and packaging proteins for secretion?
  3. During which phase of mitosis do the sister chromatids separate and move to opposite poles?
  4. In which phase of meiosis does crossing over between homologous chromosomes occur?
  5. In a population in Hardy-Weinberg equilibrium, 4% of people have a recessive condition. What is the frequency of carriers?
  6. A woman who is a carrier of an X-linked recessive disease has children with an unaffected man. What proportion of their sons are expected to be affected?
  7. Which two hormones are released from the posterior pituitary?
  8. How does antidiuretic hormone increase water reabsorption in the collecting duct?
  9. Where is the main pacemaker of the heart located?
  10. Which organ produces bile?
  11. Which cell type secretes antibodies?
  12. Which cell is a professional antigen-presenting cell that activates naive helper T cells?
  13. Cytotoxic T cells recognize antigen displayed on which molecule?
  14. Which ion flows into a neuron mainly during the depolarization phase of an action potential?
  15. What is the main effect of myelin on a neuron's axon?
  16. In the polymerase chain reaction, which step requires the highest temperature?
  17. Which technique separates DNA fragments according to their size?
  18. Which cells in the stomach secrete hydrochloric acid?
  19. Which of these is a function of the lymphatic system?
  20. Which cells produce antibodies?
  21. Which type of RNA carries amino acids to the ribosome?
  22. A neuron membrane potential becomes more negative than the resting potential. What is this called?
  23. Which chambers of the heart pump blood out to the body and lungs?
  24. Which part of the brain regulates body temperature and hunger?
  25. During which phase of meiosis does crossing over occur?
  26. Which structure in the lungs is the site of gas exchange?
  27. Which gland secretes thyroxine?
  28. What is the function of the Golgi apparatus?
  29. Which type of immunity is provided by a vaccine?
  30. Which hormone released from the posterior pituitary increases water reabsorption in the collecting duct?
  31. Which event occurs first in an action potential?
  32. Which enzyme begins the digestion of starch?
  33. Which hormone causes the uterine lining to thicken after ovulation?
  34. Which structure connects the placenta to the fetus?
  35. Which of the following describes a dominant allele?
  36. Which type of muscle is under voluntary control and striated?
  37. A cross of two heterozygous individuals (Aa x Aa) produces what ratio of genotypes?
  38. What is the role of calcium in skeletal muscle contraction?
  39. Which germ layer gives rise to the nervous system?
  40. Which ion is primarily responsible for the plateau phase of the cardiac ventricular action potential?
  41. Which vitamin deficiency causes night blindness?
  42. Which process allows bacteria to take up DNA from the environment?
  43. Which hormone is released by the adrenal medulla during the fight-or-flight response?
  44. Which receptor type is a ligand-gated ion channel?
  45. Which organelle is the site of oxidative phosphorylation?
  46. A person with blood type AB can receive red blood cells from which donors?
  47. Which phase of the cell cycle includes DNA replication?
  48. Which cytoskeletal element forms the mitotic spindle?
  49. Which cell division produces gametes?
  50. Which cell type in the pancreas secretes insulin?
  51. Which organ is the main site of bile production?
  52. Which type of cell junction allows direct passage of small molecules between adjacent cells?
  53. In a population in Hardy-Weinberg equilibrium, the frequency of the recessive allele is 0.3. What is the frequency of heterozygotes?
  54. Which structure transmits sound vibrations from the eardrum to the oval window?
  55. Where does most chemical digestion of fats occur?
  56. Which structure of the nephron is the main site of glucose reabsorption?
  57. Which blood vessel carries oxygenated blood from the lungs to the heart?
  58. Which enzyme unwinds the DNA double helix at the replication fork?
  59. Which organelle contains hydrolytic enzymes that digest worn-out cell components?
  60. Which amino acid contains a sulfhydryl group able to form disulfide bonds?
  61. In which part of the cell does glycolysis occur?
  62. Which hormone is secreted by the anterior pituitary and stimulates the thyroid?
  63. Which type of bond holds the two strands of DNA together?
  64. Which cells of the immune system present antigen on MHC class II molecules?
  65. Which stage of mitosis aligns the chromosomes at the cell's equator?
  66. Which molecule carries the genetic code out of the nucleus?
  67. Which structure of a neuron receives incoming signals from other neurons?
  68. Which ion enters the presynaptic terminal to trigger neurotransmitter release?
  69. Which organ stores bile?

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