In which cellular subcompartment does oxidative decarboxylation of pyruvate to acetyl-CoA take place?
Answer and explanation
Correct answer: B. Mitochondrial matrix
Pyruvate dehydrogenase complex resides inside the mitochondrial matrix, where pyruvate is converted to acetyl-CoA, NADH, and CO2. Glycolysis occurs in the cytosol, and beta-oxidation of very long-chain fatty acids occurs in peroxisomes.
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