Release of which mitochondrial intermembrane protein into the cytosol triggers intrinsic apoptosis?
Answer and explanation
Correct answer: C. Cytochrome c
Mitochondrial outer membrane permeabilization releases cytochrome c into the cytoplasm, where it binds Apaf-1 to form the apoptosome and activate caspase-9. Citrate synthase and respiratory complexes remain inside mitochondria.
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