Which DNA repair pathway corrects bulky helix-distorting lesions such as UV-induced thymine dimers?
Answer and explanation
Correct answer: D. Nucleotide excision repair pathway
Nucleotide excision repair recognizes and removes bulky helix-distorting adducts such as cyclobutane pyrimidine dimers. BER repairs small, non-distorting base modifications (e.g., uracil or 8-oxoguanine), and MMR corrects replication mismatches.
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