What ionic conductance is primarily responsible for establishing the negative resting membrane potential of neurons?
Answer and explanation
Correct answer: C. Outward potassium flux through non-gated leak channels
The resting membrane potential (typically -70 mV) is primarily determined by high resting permeability to K+ via non-gated background leak channels (K2P), driving the potential toward the potassium equilibrium potential (~ -90 mV).
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