What is the definition of primary amenorrhea in an adolescent female?
Answer and explanation
Correct answer: A. Absence of menses by age 15 with secondary sexual characteristics, or by age 13 without them
- Step 1: Primary amenorrhea is diagnosed when menarche has not occurred by age 15 in the presence of normal secondary sexual development (thelarche/pubarche), or by age 13 in the absence of secondary sexual characteristics.
- Step 2: Common etiologies include Turner syndrome (45,X), müllerian agenesis, and constitutional delay.
- Step 3: Secondary amenorrhea refers to cessation of established menses.
Answer
Absence of menses by age 15 with secondary sexual characteristics, or by age 13 without them.
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