Choose the most logically coherent transitional adverb for the blank: 'The experimental drug lowered blood pressure effectively; __________, adverse gastrointestinal events led to high trial attrition.'

Answer and explanation

Correct answer: A. nonetheless

  1. Step 1: Analyze relationship between clauses: Clause 1 presents a positive therapeutic benefit; Clause 2 presents negative adverse events causing dropouts.
  2. Step 2: The relationship is adversative/concessive (contrast).
  3. Step 3: 'Nonetheless' correctly introduces a contrasting counterpoint despite the preceding statement.
Answer
nonetheless.
Why not the others: 'Furthermore' indicates addition; 'consequently' indicates cause-effect; 'similarly' indicates comparison.

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