A young woman has weight loss, tremor, a diffuse goitre and exophthalmos. Which antibody is responsible?
Answer and explanation
Correct answer: A. TSH receptor stimulating antibody directed at the thyroid cell
- Step 1: Hyperthyroid symptoms with a diffuse goitre and eye signs indicate Graves disease. Step 2. The antibody stimulates the TSH receptor and drives hormone production. Answer: TSH receptor stimulating antibody. Why not the others: Anti-TPO is typical of Hashimoto thyroiditis. Anti-dsDNA relates to lupus. Anti-mitochondrial antibody relates to primary biliary cholangitis.
Practise more Internal Medicine.
Free questions with an explanation for every one, and full timed ENAM Practice (Peru National Medical Examination) mock tests.
More Internal Medicine questions
- A 58-year-old man has crushing chest pain for 40 minutes. The ECG shows ST elevation in leads II, III and aVF. Which artery is most likely o…
- Which drug is the usual first-line oral agent for a newly diagnosed adult with type 2 diabetes and normal kidney function?
- A man with diabetic ketoacidosis has glucose 28 mmol/L, pH 7.1 and serum potassium 3.0 mmol/L before any treatment. What should be done firs…
- HbA1c reflects the average blood glucose over roughly which period?
- A 62-year-old man has fatigue, microcytic anaemia and a low ferritin. He has no bleeding symptoms. What is the most appropriate next step?
- A man with heart failure has a serum potassium of 6.4 mmol/L and the ECG shows peaked T waves and a widened QRS. What is the first treatment…