How is replacement therapy with levothyroxine monitored in primary hypothyroidism?

Answer and explanation

Correct answer: D. By measuring serum TSH

  1. Step 1: In primary hypothyroidism the pituitary senses low thyroid hormone and raises TSH. Step 2. TSH therefore falls into the normal range when replacement is adequate. Answer: Serum TSH. Why not the others: Calcium is unrelated. Urine iodine reflects intake. The heart rate is a poor guide on its own.

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