Which adverse effect most typically limits statin therapy?
Answer and explanation
Correct answer: A. Muscle pain or myopathy, rarely rhabdomyolysis
- Step 1: Statins inhibit hydroxymethylglutaryl-CoA reductase and can affect muscle. Step 2. Myalgia is the commonest complaint, and creatine kinase is checked if it is severe. Answer: Myopathy. Why not the others: Tendon rupture, pulmonary fibrosis and neuropathy belong to other drugs.
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