Which drug class improves survival in heart failure with reduced ejection fraction?
Answer and explanation
Correct answer: A. Beta blockers such as bisoprolol or carvedilol, started once the patient is stable
- Step 1: Drugs that block neurohormonal activation prolong life in this condition. Step 2. ACE inhibitors, beta blockers, mineralocorticoid antagonists and SGLT2 inhibitors have mortality data. Answer: Beta blockers. Why not the others: Digoxin and diuretics give symptom relief only. Verapamil and diltiazem worsen systolic failure.
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