Which drug is the usual first-line disease-modifying agent in rheumatoid arthritis?
Answer and explanation
Correct answer: B. Methotrexate, given weekly with folic acid
- Step 1: Early rheumatoid arthritis is treated with a conventional synthetic DMARD. Step 2. Methotrexate is the anchor drug and is given once weekly with folic acid. Answer: Methotrexate. Why not the others: Allopurinol treats gout. Isoniazid treats tuberculosis. Warfarin is an anticoagulant.
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