Which team of Argentine physiologists at Houssay's institute discovered 'angiotensin' (originally hypertensin) in 1939?
Answer and explanation
Correct answer: A. Eduardo Braun-Menéndez and Juan Carlos Fasciolo, with Leloir, Muñoz, and Taquini
- Step 1: They isolated a peptide substance produced when renin acts on a blood protein, causing severe vasoconstriction. Step 2. A concurrent US team called it 'angiotonin'; both groups agreed in 1958 to name it 'angiotensin'. Answer: Eduardo Braun-Menéndez and Juan Carlos Fasciolo, with Leloir, Muñoz, and Taquini. Why not the others: The discovery led directly to modern ACE-inhibitor and ARB blood pressure medications.
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