UKMLA Applied Knowledge Test (MSRA-style single best answer) · Gastroenterology, Renal, Urology and Endocrinology

Endocrinology

13 practice questions, each with the answer and an explanation.

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Random questions from this topic, one at a time. You see the answer and the explanation straight after each one.

All 13 questions

  1. A patient has hypotension, hyponatraemia, hyperkalaemia and skin pigmentation. What is the best confirmatory test?
  2. Which combination meets the UK criteria for diagnosing diabetic ketoacidosis?
  3. A woman with Graves' disease who is 8 weeks pregnant needs an antithyroid drug. Which is preferred in the first trimester?
  4. A 45-year-old has a TSH of 8 mU/L with a normal free T4 on two occasions, and no symptoms. How is this described and managed?
  5. A patient has calcium of 3.1 mmol/L, a suppressed PTH, a lung mass and bone pain. What is the likely mechanism, and what is the initial treatment?
  6. An obese woman has a moon face, purple abdominal striae and proximal weakness. Which is the first-line screening test for Cushing syndrome?
  7. A patient with episodic headache, sweating and palpitations has hypertension and a confirmed adrenal phaeochromocytoma. Before surgery, which drug should be started first?
  8. After head injury a patient passes 8 litres of dilute urine per day. Water deprivation fails to concentrate the urine, but desmopressin does. What is the diagnosis?
  9. A man with headaches, enlarging hands and a coarse face is suspected of acromegaly. What is the diagnostic test?
  10. A woman with a pituitary adenoma has a bitemporal hemianopia and galactorrhoea, with a markedly raised prolactin. What is the first-line treatment?
  11. A patient with type 2 diabetes on metformin, an ACE inhibitor and an SGLT2 inhibitor develops vomiting and diarrhoea with dehydration. What does sick day guidance advise?
  12. Which statement about long-term management of type 1 diabetes is correct?
  13. A man with diabetes has a hot, swollen, painless foot with intact pulses and a history of neuropathy. What is the most likely diagnosis?

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