UKMLA Applied Knowledge Test (MSRA-style single best answer) · Musculoskeletal, Dermatology, Haematology, Genetics, Cancer and Palliative Care

Musculoskeletal medicine

10 practice questions, each with the answer and an explanation.

Practise Musculoskeletal medicine now

Random questions from this topic, one at a time. You see the answer and the explanation straight after each one.

All 10 questions

  1. A man has a hot, swollen first metatarsophalangeal joint. Aspirated fluid shows needle-shaped, negatively birefringent crystals under polarised light. When should urate-lowering therapy such as allopu…
  2. A feverish adult has a single hot, swollen, painful knee with a markedly restricted range of movement. What is the most appropriate first step?
  3. A 70-year-old woman with a vertebral fragility fracture is started on alendronate. Which advice should she be given?
  4. A woman with rheumatoid arthritis taking methotrexate is prescribed trimethoprim for a urinary tract infection. What is the concern?
  5. A young woman has a malar rash, arthralgia, photosensitivity and proteinuria. Which antibody is most specific for the likely diagnosis?
  6. Under the Ottawa ankle rules, which finding means an ankle X-ray series is needed?
  7. What is the first-line approach for a 62-year-old with knee osteoarthritis according to NICE?
  8. A 72-year-old woman has bilateral shoulder and hip girdle stiffness for several weeks, worse in the morning, with an ESR of 70 mm/hr and a dramatic response to low-dose prednisolone. What is the diagn…
  9. After a tibial fracture treated in a cast, a patient has severe pain unrelieved by opioids and pain on passive stretching of the toes. What is the most important management?
  10. A 24-year-old man has low back pain and stiffness that is worst in the morning and improves with exercise, with a family history of similar problems. What is the most likely diagnosis?

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