What are the sedimentation coefficients of the two ribosomal subunits in a eukaryotic 80S ribosome?
Answer and explanation
Correct answer: D. 60S large subunit and 40S small subunit
- Step 1: Eukaryotic cytosolic ribosomes have an overall sedimentation coefficient of 80S. Step 2. They are assembled from a 60S large subunit (containing 28S, 5.8S, and 5S rRNAs) and a 40S small subunit (containing 18S rRNA). Answer: 60S large subunit and 40S small subunit. Why not the others: 50S and 30S form the prokaryotic 70S ribosome; 50S/40S and 60S/30S are non-existent combinations.
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