At which stage of mitosis do sister chromatids separate completely and move toward opposite spindle poles?
Answer and explanation
Correct answer: C. Anaphase
- Step 1: Cohesin proteins holding sister chromatids are cleaved by separase at the onset of anaphase. Step 2. Kinetochore microtubules shorten, pulling daughter chromosomes toward opposite centrosomal poles during anaphase. Answer: Anaphase. Why not the others: Metaphase aligns chromosomes at equatorial plate; prophase condenses chromatin and breaks nuclear envelope; telophase reforms nuclei.
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