What specific iron-chelating agent is clinically indicated for acute Iron toxicity and chronic iron overload (hemochromatosis)?
Answer and explanation
Correct answer: A. Deferoxamine
- Step 1: Deferoxamine is a bacterial siderophore with extraordinarily high affinity for ferric iron (Fe3+). Step 2. It binds free iron to form ferrioxamine, which is excreted through the kidneys turning urine reddish-orange. Answer: Deferoxamine (Desferrioxamine). Why not the others: BAL is for arsenic/mercury; Calcium EDTA is for lead; Amyl nitrite is used in cyanide antidote kits.
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