Which cell surface molecules present endogenous peptides to cytotoxic CD8+ T lymphocytes?
Answer and explanation
Correct answer: C. MHC class I molecules
MHC class I molecules (expressed on all nucleated cells) present peptides derived from endogenous cytosolic proteins degraded by the proteasome to CD8+ cytotoxic T cells. MHC class II presents exogenous antigens to CD4+ helper T cells.
Practise more Nervous, Sensory, and Immune Systems.
Free questions with an explanation for every one, and full timed Medical University Entrance Examination (Bulgaria) mock tests.
More Nervous, Sensory, and Immune Systems questions
- What ionic conductance is primarily responsible for establishing the negative resting membrane potential of neurons?
- Which rapid ionic event underlies the steep depolarization phase (phase 0) of a neuronal action potential?
- What mechanism explains the absolute refractory period in excitable neuronal membranes?
- Why does myelination dramatically increase the conduction velocity of action potentials along axons?
- Which ion influx into the presynaptic terminal triggers exocytosis of neurotransmitter vesicles?
- Which chemical is the primary inhibitory neurotransmitter in the human adult cerebral cortex?