Which metabolic process produces lactic acid in human skeletal muscle cells during prolonged strenuous exercise when oxygen supply becomes insufficient?

Answer and explanation

Correct answer: D. Anaerobic homolactic fermentation

  1. Step 1: Determine cellular response to anaerobic conditions during intense exertion.
  2. Step 2: When electron transport chain halts due to lack of oxygen, pyruvate is reduced to lactate by lactate dehydrogenase, reoxidizing NADH back to NAD⁺ so glycolysis can continue generating ATP.
Answer
Anaerobic homolactic fermentation.
Why not the others: Alcoholic fermentation occurs in yeasts producing ethanol and CO₂; oxidative phosphorylation and beta-oxidation require abundant oxygen.

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