Which post-transcriptional RNA modification occurs in eukaryotic pre-mRNA processing prior to nuclear export?
Answer and explanation
Correct answer: B. 5' capping, 3' poly-A tail, and intron splicing
- Step 1: Eukaryotic pre-mRNA undergoes 5' capping (7-methylguanosine), 3' polyadenylation (poly-A tail), and spliceosome removal of introns with exon ligation. Answer: Addition of a 5' 7-methylguanosine cap and a 3' poly-A tail with intron splicing. Why not the others: Exons are retained (coding sequences), while introns are excised.
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