MOH Prometric · Clinical Practice & Patient Safety

Pharmacology, Dosages and Patient Management

15 practice questions, each with the answer and an explanation.

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Random questions from this topic, one at a time. You see the answer and the explanation straight after each one.

All 15 questions

  1. A physician prescribes Ceftriaxone 1 g IV daily. The reconstitution vial contains 1 g of powder. When diluted with 10 mL of sterile water, what volume delivers 500 mg?
  2. Which medication is the first-line emergency drug for an acute severe anaphylactic reaction?
  3. What is the critical laboratory parameter monitored to evaluate the therapeutic efficacy and safety of unfractionated Heparin therapy?
  4. Which antidote is administered to reverse life-threatening respiratory depression caused by Opioid overdose?
  5. In a diabetic patient presenting with tremors, diaphoresis, confusion, and blood glucose of 45 mg/dL (2.5 mmol/L), what is the immediate intervention for a conscious patient?
  6. What is the specific pharmacological antidote for Acetaminophen (Paracetamol) hepatotoxicity?
  7. Which class of antihypertensive medications is strictly contraindicated during all trimesters of pregnancy due to fetal renal dysgenesis risks?
  8. What is the therapeutic target range for serum Digoxin in adult patients with heart failure?
  9. A patient on Warfarin therapy with an INR of 7.2 presents with significant hematuria. Which agent reverses the anticoagulant effect?
  10. What early sign of Lidocaine toxicity should prompt an immediate cessation of the local anesthetic infusion?
  11. Which oral antibiotic should NOT be co-administered with antacids, calcium supplements, or milk due to chelation-induced malabsorption?
  12. A pediatric patient weighing 15 kg requires oral Paracetamol (15 mg/kg per dose). What single dose should be dispensed?
  13. A child weighing 18 kg is prescribed acetaminophen 15 mg/kg. The suspension is 160 mg per 5 mL. How many millilitres should be given?
  14. A patient on long-term lithium is started on a thiazide diuretic for hypertension. A week later she has coarse tremor, vomiting and unsteady gait. What is the most likely explanation and action?
  15. A patient who received an opioid has a respiratory rate of 6/min and is barely rousable. Naloxone is ordered. Which approach is safest?

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